This article is devoted to the problem of quality of natural science training in modern universities. The lack of readiness of Russian universities and schools for any conditions of natural science training, including online training, is discussed. The authors of the article propose the following factors as the main signs of the quality of natural science education: 1) professionalism of faculty; 2) availability of training courses, the content of which is characterized by a high degree of intra- and interprandial connectivity and includes achievements of modern research in natural sciences; 3) provision of the experimental-laboratory base with modern equipment. An additional factor is considered – digital educational environment. The article introduces indicators for each factor and proposes a way to evaluate them.